Preclinical: meaning, definitions and examples

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preclinical

 

[ priːˈklɪnɪkəl ]

Adjective
Context #1 | Adjective

medical research

Preclinical refers to the research and experimentation that occurs before clinical trials involve human participants. This stage typically involves laboratory experiments, animal studies, and other forms of scientific testing. It aims to gather initial efficacy and safety data for new drugs or treatments.

Synonyms

developmental, experimental, preliminary

Examples of usage

  • The drug successfully passed the preclinical trials.
  • Preclinical studies are essential for drug approval.
  • Researchers are conducting preclinical tests on a new therapy.

Translations

Translations of the word "preclinical" in other languages:

🇵🇹 pré-clínico

🇮🇳 पूर्व-कलिनिक

🇩🇪 präklinisch

🇮🇩 pra-klinis

🇺🇦 дослідження перед клінічними випробуваннями

🇵🇱 przedkliniczny

🇯🇵 前臨床の

🇫🇷 préclinique

🇪🇸 preclínico

🇹🇷 klinik öncesi

🇰🇷 전임상

🇸🇦 قبل السريرية

🇨🇿 předklinický

🇸🇰 predklinický

🇨🇳 临床前的

🇸🇮 predklinični

🇮🇸 fyrirklínísk

🇰🇿 передклиникалық

🇬🇪 პრეკლინიკური

🇦🇿 preklinik

🇲🇽 preclínico

Etymology

The term 'preclinical' is derived from the prefix 'pre-' meaning 'before', and 'clinical', which originates from the Greek word 'klinikos', meaning 'pertaining to the bedside'. The term has gained prominence in the fields of medicine and pharmacology as the understanding of drug development processes has evolved. Its use became more widespread in the late 20th century, particularly as the pharmaceutical industry began to prioritize rigorous testing and validation of drugs before they reach human trials. As research methodologies advanced, 'preclinical' came to denote a specific phase in the drug development pipeline, emphasizing the importance of ensuring safety and efficacy before any clinical studies involving humans can commence.