Histamine Meaning: Definition, Examples, and Translations

๐Ÿ’Š
Add to dictionary

histamine

[หˆhษชstษ™หŒmiหn ]

Definition

Context #1 | Noun

biochemistry

Histamine is a biogenic amine involved in local immune responses, regulation of physiological functions in the gut, and acts as a neurotransmitter. It plays a key role in the body's immune response to allergens, contributing to swelling and itching. In addition, histamine is involved in gastric acid secretion.

Synonyms

autoimmune mediator, biogenic amine, histamine H1 receptor.

Examples of usage

  • Histamine levels can increase during an allergic reaction.
  • Antihistamines are commonly used to relieve symptoms of allergies.
  • Histamine is released by mast cells in response to allergens.

Translations

To see the translation, please select a language from the options available.

Interesting Facts

Science

  • Histamine is produced by immune cells called mast cells and basophils, playing a key role in the body's response to allergens.
  • It helps regulate functions like stomach acid production, showing that it's important for digestion as well.

Health

  • Antihistamines are medications that block the effects of histamine, commonly used to treat allergies and hay fever.
  • An excess of histamine can lead to allergies or hypersensitivity reactions, making it important to maintain balance in the body.

Pop Culture

  • Histamine's effects have been referenced in various media to depict allergic reactions, emphasizing the plight of allergy sufferers.
  • Allergies, influenced by histamine, are a common theme in humorous stories, showcasing everyday challenges like sneezing during a date.

Food Science

  • Certain fermented foods, like aged cheese and wine, contain high levels of histamine, which can affect people intolerant to it.
  • Cooking can reduce histamine levels in some foods, thus influencing dietary choices for those with sensitivities.

Origin of 'histamine'

Main points about word origin

  • The name comes from 'histidine,' an amino acid involved in its production, combined with 'amine,' meaning it contains nitrogen.
  • Histamine was first discovered in the early 20th century by a scientist named Dale, who explored its effects in the body.

The term 'histamine' was coined in 1910 by the French pharmacologist Claude Bernard as he studied its effects on the physiological processes in living organisms. The name is derived from the Greek root 'histos,' referring to the tissue, and the suffix '-amine,' indicating its chemical structure as an amine. Its discovery linked to its role in inflammatory responses was significantly expanded in the 20th century, particularly through the work of researchers who identified its systemic effects. Over the years, the understanding of histamine evolved, uncovering its roles in various bodily functions beyond allergies, such as its involvement in gastric acid secretion and neurotransmission. This compound has led to the development of various medications, particularly antihistamines, which counteract its effects in allergic reactions and other conditions.


Word Frequency Rank

At position #14,996, this word is part of sophisticated English vocabulary. It's useful for academic or professional contexts where precise language is needed.