Thymidine: meaning, definitions and examples
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thymidine
[ˈθaɪmɪdiːn ]
Definition
Context #1 | Noun
biochemistry, genetics
Thymidine is a nucleoside component of DNA, consisting of a thymine molecule attached to a deoxyribose sugar. It plays a crucial role in the structure of DNA and is essential for DNA replication and repair. Thymidine can also be found in certain biochemical reactions as an intermediate.
Synonyms
deoxythymidine, thymine nucleoside.
Examples of usage
- Thymidine is incorporated into the DNA strand during replication.
- The synthesis of thymidine is essential for cell division.
- Researchers studied the effects of thymidine on DNA repair mechanisms.
Interesting Facts
Etymology
- The word 'thymidine' comes from 'thymus' (a part of the immune system) and 'nucleoside', indicating its role in DNA structure.
- Thymidine was first isolated from the nucleic acids in the 19th century, reflecting advances in biochemistry.
- The name highlights its origin from thymine, a nitrogenous base found in DNA.
Biochemistry
- Thymidine is one of the four nucleosides that make up DNA, alongside adenine, cytosine, and guanine.
- It plays a crucial role in cellular processes, particularly during DNA synthesis and repair.
- Thymidine forms base pairs with adenine when DNA strands bond together, helping maintain the structure of our genetic material.
Medicine
- Thymidine analogs are being studied as potential treatments for certain types of cancer and viral infections.
- In HIV research, thymidine was one of the first drugs used to treat the infection by inhibiting viral replication.
- Research has linked altered thymidine metabolism with various diseases, highlighting its significance in health.
Genetics
- Thymidine plays a role in DNA replication, which is essential for cell division and growth.
- Mutations in thymidine can lead to changes in genetic information, which can cause diseases or disorders.
- It is also crucial for maintaining the stability of genetic information across generations.
Arts and Culture
- Thymidine doesn't just influence biology; it also sparks creativity in biographical art, with artists exploring themes of life and DNA.
- The impact of genetics on identity has been a topic in modern literature and film, reflecting society's interest in the building blocks of life.
- Artists and writers have drawn inspiration from the science of life, using concepts like thymidine to express themes of mystery and existence.