Rotamer: meaning, definitions and examples

🔄

Add to dictionary

rotamer

[ ˈroʊtəmər ]

Noun

^{Context #1 | Noun}

conformational analysis

A rotamer is a specific conformation of a molecule, typically a protein, resulting from the rotation of specific bonds. Rotamers are important in understanding the structure and function of biomolecules.

Synonyms

conformation, conformer.

Which Synonym Should You Choose?

Word	Description / Examples
rotamer	Used in the context of chemistry and molecular biology to describe one of the possible spatial arrangements of atoms in a molecule that can be interconverted by rotation around a single bond. Scientists studied the different rotamers to understand the molecule's behavior better. The protein's function can change depending on the rotamer it adopts.
conformer	Refers to any of the spatial arrangements that a molecule can adopt due to rotation around single bonds. It is often used in discussions of molecular flexibility and energy states. The molecule exists in multiple conformers, each with different energies. By analyzing the conformers, researchers can predict the most stable structure.
conformation	Used in chemistry and biology to describe the spatial arrangement of atoms in a molecule that can be interconverted by rotations around single bonds without breaking any bonds. The drug's conformation is crucial for its biological activity. Different conformations of the enzyme can affect its binding with substrates.

Word

Description / Examples

rotamer

Used in the context of chemistry and molecular biology to describe one of the possible spatial arrangements of atoms in a molecule that can be interconverted by rotation around a single bond.

Scientists studied the different rotamers to understand the molecule's behavior better.
The protein's function can change depending on the rotamer it adopts.

conformer

Refers to any of the spatial arrangements that a molecule can adopt due to rotation around single bonds. It is often used in discussions of molecular flexibility and energy states.

The molecule exists in multiple conformers, each with different energies.
By analyzing the conformers, researchers can predict the most stable structure.

conformation

Used in chemistry and biology to describe the spatial arrangement of atoms in a molecule that can be interconverted by rotations around single bonds without breaking any bonds.

The drug's conformation is crucial for its biological activity.
Different conformations of the enzyme can affect its binding with substrates.

Examples of usage

The rotamer of a side chain in a protein can affect its interactions with other molecules.
Scientists use computational methods to predict the most stable rotamers of a molecule.
Understanding rotamers is crucial for drug design and molecular modeling.

Translations

Translations of the word "rotamer" in other languages:

🇵🇹 rotâmero

🇮🇳 रोटामर

🇩🇪 Rotamer

🇮🇩 rotamer

🇺🇦 ротамер

🇵🇱 rotamer

🇯🇵 ロタマー

🇫🇷 rotamère

🇪🇸 rotámero

🇹🇷 rotamer

🇰🇷 로타머

🇸🇦 روتامير

🇨🇿 rotamer

🇸🇰 rotamer

🇨🇳 旋转异构体

🇸🇮 rotamer

🇮🇸 rotamer

🇰🇿 ротамер

🇬🇪 როტამერი

🇦🇿 rotamer

🇲🇽 rotámero

Etymology

The term 'rotamer' originated in the field of conformational analysis, which studies the different spatial arrangements of atoms in molecules. It was first introduced in the 1960s as a way to describe the various conformations that molecules can adopt due to the rotation of specific bonds. Rotamers play a significant role in structural biology, especially in understanding the flexibility and dynamics of biomolecules.