Refolding: meaning, definitions and examples

๐Ÿ”„
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refolding

 

[ rษชหˆfoสŠldษชล‹ ]

Verb
Context #1 | Verb

biological process

Refolding refers to the process of restoring a protein or other biological molecule to its correct three-dimensional structure after it has been denatured or unfolded. This process is crucial in biological systems for maintaining the functionality of proteins, enzymes, and other macromolecules.

Synonyms

reconfiguration, reformation, restoration

Examples of usage

  • The refolding of the enzyme was essential for its activity.
  • Scientists studied the refolding process to understand protein stability.
  • After heat shock, the cell's machinery assists in refolding proteins.

Translations

Translations of the word "refolding" in other languages:

๐Ÿ‡ต๐Ÿ‡น refazendo

๐Ÿ‡ฎ๐Ÿ‡ณ เคซเคฟเคฐ เคธเฅ‡ เคฎเฅ‹เคกเคผเคจเคพ

๐Ÿ‡ฉ๐Ÿ‡ช Umstrukturierung

๐Ÿ‡ฎ๐Ÿ‡ฉ pengulangan

๐Ÿ‡บ๐Ÿ‡ฆ ะฟะตั€ะตั„ะพั€ะผัƒะฒะฐะฝะฝั

๐Ÿ‡ต๐Ÿ‡ฑ przeformuล‚owanie

๐Ÿ‡ฏ๐Ÿ‡ต ๅ†ๆŠ˜ใ‚ŠใŸใŸใฟ

๐Ÿ‡ซ๐Ÿ‡ท repliage

๐Ÿ‡ช๐Ÿ‡ธ repliegue

๐Ÿ‡น๐Ÿ‡ท yeniden katlama

๐Ÿ‡ฐ๐Ÿ‡ท ๋‹ค์‹œ ์ ‘๊ธฐ

๐Ÿ‡ธ๐Ÿ‡ฆ ุฅุนุงุฏุฉ ุงู„ุทูŠ

๐Ÿ‡จ๐Ÿ‡ฟ pล™eloลพenรญ

๐Ÿ‡ธ๐Ÿ‡ฐ preformulovanie

๐Ÿ‡จ๐Ÿ‡ณ ้‡ๆ–ฐๆŠ˜ๅ 

๐Ÿ‡ธ๐Ÿ‡ฎ preoblikovanje

๐Ÿ‡ฎ๐Ÿ‡ธ endurhรถnnun

๐Ÿ‡ฐ๐Ÿ‡ฟ า›ะฐะนั‚ะฐ ะถะธะฝะฐา›ั‚ะฐัƒ

๐Ÿ‡ฌ๐Ÿ‡ช แƒ›แƒ”แƒแƒ แƒ”แƒ“ แƒ“แƒแƒ™แƒ”แƒชแƒ•แƒ

๐Ÿ‡ฆ๐Ÿ‡ฟ tษ™krar qatlama

๐Ÿ‡ฒ๐Ÿ‡ฝ repliegue

Etymology

The term 'refolding' originates from the combination of the prefix 're-' signifying back or again, and 'folding,' referring to the process of forming a particular shape or configuration. The first known usages relate to the study of protein chemistry in the late 20th century when researchers began to explore how proteins could lose and regain their functional forms. This became increasingly relevant with advancements in biotechnology and the understanding of molecular biology. The concept exemplified the complex nature of protein dynamics and its impact on cellular functions. Refolding mechanisms have since been extensively researched, leading to insights into diseases related to protein misfolding and the development of therapies aimed at correcting these misfolded proteins.

Word Frequency Rank

Ranking #35,605, this word is encountered relatively rarely in everyday English. It might appear in literary works or specialized texts but isn't essential for general communication.