Refolding: meaning, definitions and examples
๐
refolding
[ rษชหfoสldษชล ]
biological process
Refolding refers to the process of restoring a protein or other biological molecule to its correct three-dimensional structure after it has been denatured or unfolded. This process is crucial in biological systems for maintaining the functionality of proteins, enzymes, and other macromolecules.
Synonyms
reconfiguration, reformation, restoration
Examples of usage
- The refolding of the enzyme was essential for its activity.
- Scientists studied the refolding process to understand protein stability.
- After heat shock, the cell's machinery assists in refolding proteins.
Translations
Translations of the word "refolding" in other languages:
๐ต๐น refazendo
๐ฎ๐ณ เคซเคฟเคฐ เคธเฅ เคฎเฅเคกเคผเคจเคพ
๐ฉ๐ช Umstrukturierung
๐ฎ๐ฉ pengulangan
๐บ๐ฆ ะฟะตัะตัะพัะผัะฒะฐะฝะฝั
๐ต๐ฑ przeformuลowanie
๐ฏ๐ต ๅๆใใใใฟ
๐ซ๐ท repliage
๐ช๐ธ repliegue
๐น๐ท yeniden katlama
๐ฐ๐ท ๋ค์ ์ ๊ธฐ
๐ธ๐ฆ ุฅุนุงุฏุฉ ุงูุทู
๐จ๐ฟ pลeloลพenรญ
๐ธ๐ฐ preformulovanie
๐จ๐ณ ้ๆฐๆๅ
๐ธ๐ฎ preoblikovanje
๐ฎ๐ธ endurhรถnnun
๐ฐ๐ฟ าะฐะนัะฐ ะถะธะฝะฐาัะฐั
๐ฌ๐ช แแแแ แแ แแแแแชแแ
๐ฆ๐ฟ tษkrar qatlama
๐ฒ๐ฝ repliegue
Etymology
The term 'refolding' originates from the combination of the prefix 're-' signifying back or again, and 'folding,' referring to the process of forming a particular shape or configuration. The first known usages relate to the study of protein chemistry in the late 20th century when researchers began to explore how proteins could lose and regain their functional forms. This became increasingly relevant with advancements in biotechnology and the understanding of molecular biology. The concept exemplified the complex nature of protein dynamics and its impact on cellular functions. Refolding mechanisms have since been extensively researched, leading to insights into diseases related to protein misfolding and the development of therapies aimed at correcting these misfolded proteins.