Pathogenesis Meaning: Definition, Examples, and Translations
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pathogenesis
[ˌpæθəˈdʒɛnɪsɪs ]
Definition
medical science
Pathogenesis refers to the biological mechanism that leads to a disease or pathological condition. It encompasses the origin and development of a disease, shedding light on how an infectious agent or environmental factor interacts with the host's body to alter normal physiological functions.
Synonyms
disease mechanism, etiology, pathophysiology.
Examples of usage
- Understanding the pathogenesis of the disease can help in developing targeted therapies.
- Research into the pathogenesis of autoimmune disorders is crucial for new treatment approaches.
- The pathogenesis of cancer involves a series of genetic mutations leading to uncontrolled cell growth.
Translations
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Origin of 'pathogenesis'
The term 'pathogenesis' is derived from the Greek words 'pathos', meaning 'suffering or disease', and 'genesis', meaning 'creation or origin'. It first emerged in the medical literature in the late 19th century and has since been used to describe the processes that lead to various diseases. Over time, pathogenesis has become a crucial concept in fields like microbiology, immunology, and pathology, allowing scientists and medical professionals to understand how diseases originate and evolve. The study of pathogenesis has led to significant advancements in medical research, enabling the development of treatments and preventative measures for a wide range of health conditions.