Immunogenicity: meaning, definitions and examples
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immunogenicity
[ɪˌmjunəˈdʒɛnɪsɪti ]
Definition
biological response
Immunogenicity refers to the ability of a substance, such as an antigen or vaccine, to provoke an immune response in the body. It is a crucial factor in the development of vaccines and therapeutics, as a high level of immunogenicity is often desired to ensure effective protection against diseases. Factors influencing immunogenicity include the nature of the antigen, the dose administered, and the route of administration.
Synonyms
antigenicity, immune response capability, reactogenicity.
Examples of usage
- The immunogenicity of the new vaccine was tested in several clinical trials.
- Hereditary factors can influence individual immunogenicity.
- The immunogenicity of proteins can vary based on their molecular structure.
Interesting Facts
Etymology
- The term 'immunogenicity' comes from the combination of 'immuno-' relating to the immune system and '-genic' meaning producing or causing.
- It reflects the scientific understanding that certain substances can trigger an immune response in the body.
Science
- Immunogenicity is crucial in developing vaccines, as a successful vaccine must elicit a strong immune response.
- Factors influencing immunogenicity include the structure of the antigen, the presence of adjuvants, and the method of delivery.
- Some diseases can have varying levels of immunogenicity, which impacts how effectively they can be fought off by the immune system.
Healthcare
- Understanding immunogenicity is vital in personalized medicine, where treatments are tailored based on an individual's immune response.
- Researchers are studying immunogenicity to improve therapeutic proteins, making them more effective and minimizing adverse reactions.
History
- The concept of immunogenicity gained significant attention in the 20th century during the development of the first safe vaccines.
- Pioneering work in the field was done by scientists like Louis Pasteur, who laid the groundwork for understanding immune responses.
Pop Culture
- Immunogenicity is sometimes mentioned in popular media, particularly in documentaries about vaccines and infectious diseases.
- It often arises in discussions of public health and safety, especially during outbreaks where vaccination plays a key role.
Translations
Translations of the word "immunogenicity" in other languages:
🇵🇹 imunogenicidade
🇮🇳 प्रतिरक्षितता
🇩🇪 Immunogenität
🇮🇩 imunogenisitas
🇺🇦 імуногенність
🇵🇱 immunogenność
🇯🇵 免疫原性
🇫🇷 immunogénicité
🇪🇸 inmunogenicidad
🇹🇷 immunojenite
🇰🇷 면역원성
🇸🇦 المناعة
🇨🇿 imunogenita
🇸🇰 imunogenicita
🇨🇳 免疫原性
🇸🇮 imunogenost
🇮🇸 ónæmi
🇰🇿 иммуногендік
🇬🇪 იმუნოგენურობა
🇦🇿 immunogeniklik
🇲🇽 inmunogenicidad