Sulfonamide Meaning: Definition and Examples
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sulfonamide
[sʌl'fɒnəmaɪd ]
Definition
pharmaceutical compound
Sulfonamides are a group of synthetic antibiotics that contain the sulfonamide group. They work by inhibiting the growth of bacteria, making them effective in treating a variety of infections. Sulfonamides were among the first antibiotics to be discovered and have historically been used to treat bacterial infections.
Synonyms
antibacterial agent, sulfa drug.
Examples of usage
- The doctor prescribed a sulfonamide for the patient's infection.
- Sulfonamides were once widely used in the treatment of pneumonia.
- Due to the rise of antibiotic resistance, sulfonamides are less commonly used now.
- The discovery of sulfonamides marked a significant advancement in medical treatment.
Interesting Facts
Historical Origins
- Sulfonamides were first discovered in the early 20th century, marking the beginning of modern antibiotics.
- The first sulfonamide drug, Prontosil, was used successfully in the late 1930s to treat infections in World War II.
Science
- This compound works by mimicking substances needed by bacteria to grow, preventing their reproduction.
- Many sulfonamides are synthesized in laboratories, showcasing the advancements in chemistry and pharmaceutical development.
Literature
- The impact of sulfonamides on medicine has been discussed in numerous scientific journals and literature since their discovery.
- They are sometimes mentioned in literary works focused on medical advancements and ethical debates in health care.
Pop Culture
- Sulfonamides' introduction changed the portrayal of doctors and medicine in films, emphasizing their battle against infections.
- They are sometimes featured in TV shows that highlight medical breakthroughs and their impact on society.
Psychology
- The success of sulfonamides helped boost public confidence in antibiotics, positively influencing mental health during health crises.
- Their use during epidemics often relates to psychological studies exploring how advancements in medicine affect societal morale.
Origin of 'sulfonamide'
The term 'sulfonamide' comes from the combination of 'sulfon-' which is derived from sulfonic acid, and '-amide' which indicates a derivative of amine. The first sulfonamide, sulfanilamide, was synthesized in the early 20th century and became commercially available in the 1930s. It was discovered that these compounds could effectively inhibit bacterial growth, leading to the development of a new class of antibiotics. The importance of sulfonamides in medicine became prominent during World War II, as they were used to treat soldiers' infections. Despite their initial widespread use, the advent of penicillin and other antibiotics eventually overshadowed sulfonamides, although they remain relevant in specific cases of treatment today.