Reserpine: meaning, definitions and examples

Etymology

• The name 'reserpine' comes from the Rauwolfia serpentina plant, where this substance was first sourced.
• The root of the word 'serpentina' relates to 'snake,' as the plant has a snake-like appearance when it grows.
• This plant was traditionally used in Ayurvedic medicine for centuries before its substance was isolated.

Historical Use

• In the mid-20th century, reserpine was one of the first medications used to treat high blood pressure and psychiatric conditions.
• It was commonly used in mental health treatments before the development of modern antidepressants.
• Researchers found that the substance had sedative effects, which led to its popularity in managing anxiety-related conditions.

Science

• Reserpine works by affecting neurotransmitters in the brain, specifically serotonin and norepinephrine, which help regulate mood and stress.
• It can also act on the peripheral nervous system, impacting blood pressure due to its calming effects.
• Studies have shown that this drug can lead to significant changes in mood and anxiety levels for patients.

Cultural Impact

• Reserpine has been featured in discussions about 'natural' versus 'synthetic' drugs, highlighting its herbal origins.
• It sparked interest in ethnopharmacology, leading to further studies on plants used in traditional medicine.
• It was part of the larger movement in the 1950s and 60s focusing on how psychological disorders were treated—transitioning from purely behavioral methods to incorporating pharmacological solutions.

Literature

• Reserpine's calming effects have made it a subject in various books discussing mental health treatments.
• It has appeared in case studies showcasing its impact on the treatment of anxiety, depression, and hypertension.
• Authors have drawn parallels between historical herbal treatments and modern pharmacology, using reserpine as a key example.

At rank #25,115, this word represents specialized academic or technical vocabulary. It's less frequently encountered but may be valuable in specific contexts.

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• 25112 brash
• 25113 obviating
• 25114 tote
• 25115 reserpine
• 25116 myrrh
• 25117 smuggle
• 25118 protoplasmic
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