Phosphorothioate: meaning, definitions and examples
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phosphorothioate
[ ˌfɒsfəroʊˈθaɪeɪt ]
chemistry term
Phosphorothioates are organophosphorus compounds that contain a phosphorus atom bonded to a sulfur atom instead of an oxygen atom. They are often used in various chemical and biological applications, including as components in pesticides and as tools in genetic research.
Synonyms
organophosphate, phosphorothioate esters
Examples of usage
- Phosphorothioates can inhibit certain enzymes.
- The study focused on the synthesis of phosphorothioate derivatives.
- Researchers used phosphorothioates in their experiments to modify gene expression.
Translations
Translations of the word "phosphorothioate" in other languages:
🇵🇹 fosforotioato
🇮🇳 फॉस्फोरोटीओट
🇩🇪 Phosphorothioat
🇮🇩 fosforotioat
🇺🇦 фосфоротіоат
🇵🇱 fosforotioat
🇯🇵 リン酸チオエステル
🇫🇷 phosphorothioate
🇪🇸 fosforotioato
🇹🇷 fosforotioat
🇰🇷 인산티오에스터
🇸🇦 فوسفونوتيوات
🇨🇿 fosforothioát
🇸🇰 fosforotioát
🇨🇳 磷硫酸酯
🇸🇮 fosforotioat
🇮🇸 fosforotíóat
🇰🇿 фосфоротиоат
🇬🇪 ფოსფოროთიოატი
🇦🇿 fosforotioat
🇲🇽 fosforotioato
Etymology
The term phosphorothioate originates from the combination of 'phospho-', relating to the phosphorus atom, and 'thioate', which indicates the presence of sulfur in the chemical structure. The development of phosphorothioate compounds began in the mid-20th century as scientists explored variations of organophosphate structures to improve their efficacy in various applications, particularly in agriculture and biochemistry. As understanding of these compounds grew, their utility expanded into molecular biology, where they are often employed in the design of modified nucleotides for use in antisense oligonucleotide therapy and RNA research. The ability to substitute oxygen with sulfur in phosphorus compounds has opened new pathways for innovation in both environmental and medical fields.