Glycogenin: meaning, definitions and examples
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glycogenin
[ ˈɡlaɪkəʤɪnɪn ]
biochemistry
Glycogenin is a protein that serves as the primer for glycogen synthesis. It catalyzes the addition of glucose molecules to itself, forming a short chain that acts as a starting point for the more extensive glycogen polymer. This protein is essential for the proper storage of glucose in the body.
Examples of usage
- Glycogenin initiates glycogen synthesis.
- Mutations in glycogenin can affect energy storage.
- Research on glycogenin helps understand diabetes.
- Glycogenin is crucial in muscle physiology.
Etymology
The term 'glycogenin' is derived from the Greek word 'glycy', meaning sweet, and 'genes', indicating creation or origin. It was first identified in the mid-20th century during investigations into glycogen metabolism. As scientists studied the structure and function of glycogen as a polysaccharide that plays a significant role in energy storage in animals, they recognized the importance of glycogenin as the core protein. Its name reflects its foundational role in the synthesis of glycogen, highlighting its biochemical relevance in understanding metabolic pathways.