Denature: meaning, definitions and examples

chemical process

To denature means to modify the molecular structure of a substance, usually a protein, by applying an external stressor, such as heat or chemical agents. This alteration results in a loss of its natural structure and function. Denaturation is a common phenomenon in cooking, where heat causes the proteins in food to unfold and lose their biological properties. It is also significant in laboratory processes, particularly in DNA and protein studies, where the denaturation of DNA strands is essential for various techniques such as PCR. Although denaturation often renders the original compound inactive or less effective, in some cases, it can also create new properties through reconfiguration.

alter, deform, disorganize

Examples of usage

• Cooking meat can denature proteins, making it easier to digest.

• Denaturing enzymes can halt a biochemical reaction.

• Heat denaturation occurs when proteins are exposed to high temperatures.